COVID-19 and Hepatitis a Coinfection: A Case Report
Ali Mehri,
Sepideh Hasanzadeh,
Kiarash Ghazvini,
Mahnaz Mozdurian
Issue:
Volume 2, Issue 3, September 2023
Pages:
16-19
Received:
5 January 2023
Accepted:
13 July 2023
Published:
24 July 2023
Abstract: Elevated levels of liver enzymes have been identified as a common manifestation of coronavirus infection. However, it is essential to recognize that abnormal liver enzyme elevations in COVID-19 patients can also be attributed to acute hepatitis. This case report presents a clinical scenario involving a 61-year-old female patient who exhibited typical symptoms of COVID-19, including fever, nausea, anorexia, and abdominal pain. Initially, the suspicion was solely focused on COVID-19 infection. Nevertheless, subsequent investigation utilizing the acute hepatitis panel examination unveiled positive reactivity to HAV IgM, indicating a concomitant Hepatitis A virus coinfection. Throughout the course of hospitalization, the patient's clinical condition exhibited gradual improvement, leading to her discharge with an oxygen saturation level (Spo2%) exceeding 90%. Follow-up examinations conducted in the outpatient setting demonstrated the restoration of normal liver enzyme levels. This case serves as an exemplification of hepatitis coinfections, underscoring the diagnostic challenges associated with distinguishing between these two infectious conditions. It highlights the paramount importance of accurate diagnosis, preventive strategies, and optimal management approaches to effectively address such complex comorbidities. By recognizing the significance of precise diagnosis, comprehensive prevention, and appropriate management, healthcare professionals can navigate COVID-19 and hepatitis coinfections more effectively. This case report serves as a valuable reminder of the multifaceted nature of viral infections and underscores the need for a holistic approach to patient care when encountering overlapping symptomatology.
Abstract: Elevated levels of liver enzymes have been identified as a common manifestation of coronavirus infection. However, it is essential to recognize that abnormal liver enzyme elevations in COVID-19 patients can also be attributed to acute hepatitis. This case report presents a clinical scenario involving a 61-year-old female patient who exhibited typic...
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Castleman Disease Versus Generalized Tuberculosis: A Case of Fever of Unknown Origin
Edgard Niño Morin,
Daniel Sánchez Morillos,
Rafael Barreda Celis
Issue:
Volume 2, Issue 3, September 2023
Pages:
20-23
Received:
14 July 2023
Accepted:
18 August 2023
Published:
28 August 2023
Abstract: Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis; it has a high prevalence in developing countries such as Peru. Although its most frequent clinical presentation is pulmonary, but it can damage any organ and have multisystem clinical manifestations. The gold standard for its diagnosis is the finding of the bacteria in the culture; however, the result of the same can take several weeks. We present the case of a 25 year old female patient with no significant clinical history, who was admitted due to various symptoms and signs, which was classified as fever of unknown origin after several weeks of studies and inconclusive test results. She presented multisystem involvement: lymph nodes, hepatic, gastrointestinal, hematological, pleural, and pulmonary. A biopsy of cervical lymphadenopathy was performed, and the pathology report was conclusive with Hyaline vascular variant Castleman's disease; however, the gastric aspirate culture study was positive for tuberculosis. A bibliographic search was carried out on the relationship between these two entities, finding that the diagnosis of tuberculosis rules out Castleman's disease. The patient received tuberculosis treatment for 6 months, with which she presented progressive improvement of clinical manifestations. In developing patients, it is important to consider that infectious diseases such as tuberculosis can have a very varied clinical presentation and multisystem involvement, which is why they should always be considered before other more rare ones.
Abstract: Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis; it has a high prevalence in developing countries such as Peru. Although its most frequent clinical presentation is pulmonary, but it can damage any organ and have multisystem clinical manifestations. The gold standard for its diagnosis is the finding of the bacteria in the ...
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